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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1C All Species: 16.06
Human Site: S817 Identified Species: 25.24
UniProt: O43896 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43896 NP_006603.2 1103 122947 S817 E E G G G A G S G G G S E E G
Chimpanzee Pan troglodytes XP_511296 1097 122335 S811 E E G G G A G S G G G S E E G
Rhesus Macaque Macaca mulatta XP_001117788 1214 134234 S928 E E G G G A G S G G G S E E G
Dog Lupus familis XP_546571 1191 131317 G904 E E G G S S G G G G E E G A R
Cat Felis silvestris
Mouse Mus musculus O35071 1100 122416 G817 E E G C G G G G G G S E E G A
Rat Rattus norvegicus O35787 1097 122315 G814 E E G C G G G G G G G E E G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509769 1770 199343 T903 D A G S D A G T E E G S D L F
Chicken Gallus gallus XP_417608 1757 197902 T903 D T G S D A G T E E G S D L F
Frog Xenopus laevis Q91784 1226 138905 E887 K V A G S K L E S S V K Q N R
Zebra Danio Brachydanio rerio XP_699380 1180 133432 E817 G E E E G D R E D R I A A A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 V1136 G E Y V P S V V E H S D D L P
Honey Bee Apis mellifera XP_397276 1682 191012 S948 D D I G D A D S G R G D S S V
Nematode Worm Caenorhab. elegans P23678 1584 179603 K896 E D F L K S H K N G E T S D S
Sea Urchin Strong. purpuratus P46872 699 78679 K475 E K L N A I Q K K L I V G G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 E704 A L K N S E T E H L K A L V D
Conservation
Percent
Protein Identity: 100 99 89.6 87.7 N.A. 94.1 92.7 N.A. 38.1 38.7 23.9 60.4 N.A. 30.7 36.2 30.3 27.6
Protein Similarity: 100 99 89.9 89.3 N.A. 95.5 94.6 N.A. 48.6 48.4 42.3 71.8 N.A. 42.8 47.6 43.5 41
P-Site Identity: 100 100 100 46.6 N.A. 53.3 60 N.A. 33.3 33.3 6.6 13.3 N.A. 6.6 33.3 13.3 6.6
P-Site Similarity: 100 100 100 53.3 N.A. 53.3 60 N.A. 53.3 53.3 20 20 N.A. 20 46.6 40 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 43.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 7 40 0 0 0 0 0 14 7 14 20 % A
% Cys: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 14 0 0 20 7 7 0 7 0 0 14 20 7 7 % D
% Glu: 54 54 7 7 0 7 0 20 20 14 14 20 34 20 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 14 % F
% Gly: 14 0 54 40 40 14 54 20 47 47 47 0 14 20 20 % G
% His: 0 0 0 0 0 0 7 0 7 7 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 7 0 0 0 0 14 0 0 0 0 % I
% Lys: 7 7 7 0 7 7 0 14 7 0 7 7 0 0 0 % K
% Leu: 0 7 7 7 0 0 7 0 0 14 0 0 7 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 14 0 0 0 0 7 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 14 0 0 0 0 14 % R
% Ser: 0 0 0 14 20 20 0 27 7 7 14 34 14 7 7 % S
% Thr: 0 7 0 0 0 0 7 14 0 0 0 7 0 0 0 % T
% Val: 0 7 0 7 0 0 7 7 0 0 7 7 0 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _